Heerfordt’s syndrom – a rare manifestation of sarcoidosis from an ENT perspective
Authors:
L. Dostálová
; D. Kalfeřt
; A. Fíková
; M. Kuchař
; J. Plzák
Authors‘ workplace:
Klinika otorinolaryngologie a chirurgie hlavy a krku 1. LF UK a FN v Motole, Praha
Published in:
Otorinolaryngol Foniatr, 72, 2023, No. 1, pp. 33-35.
Category:
Case Reports
doi:
https://doi.org/10.48095/ccorl202333
Overview
Sarcoidosis is a systemic granulomatous disease that mainly affects the pulmonary and lymphatic systems. In its rare, acute forms, it can manifest as Lofgren’s syndrome (combination of erythema nodosum, bilateral pulmonary hilar lymphadenopathy, joint pain, fever and general symptoms) and even more rarely as Heerfordt’s syndrome (combination of fever, anterior uveitis, bilateral edema of the parotid area and uni or bilateral facial nerve paresis). Although this diagnosis is rare, it belongs to the differential diagnosis of sudden paresis of the facial nerve and swelling of the parotic area. In our case report, we describe Heerfordt’s syndrome in a 50-year-old woman. The pathophysiology, symptomatology, diagnosis, and treatment of this rare syndrome are discussed.
Keywords:
Sarcoidosis – facial nerve paresis – uveoparotid fever
Sources
1. Maharaj S, Brown M, Seegobin K et al. Sarcoidosis presenting with facial swelling (Heerfordt syndrome). Clin Case Rep 2018; 6 (10): 2023–2024. Doi: 10.1002/ccr3.1741.
2. Fujiwara K, Furuta Y, Fukuda S. Two Cases of Heerfordt‘s Syndrome: A Rare Manifestation of Sarcoidosis. Case Rep Otolaryngol 2016; 2016: 3642735. Doi: 10.1155/2016/3642735.
3. Chappity P, Kumar R, Sahoo AK. Heerfordt‘s Syndrome Presenting with Recurrent Facial Nerve Palsy: Case report and 10-year literature review. Sultan Qaboos Univ Med J 2015; 15 (1): e124–e128.
4. McGee J, Minagar A. Heerfordt‘s Syndrome: An interesting and under-recognised manifestation of sarcoidosis. Sultan Qaboos Univ Med J 2015; 15 (1): e7–8. Doi:
5. Ramachandran V, Haidari W, Ahn C et al. Uveoparotid fever as a presentation of sarcoidosis. Proc (Bayl Univ Med Cent) 2019; 32 (4): 616–618. Doi: 10.1080/08998280.2019.1624107.
6. Denny MC, Fotino AD. The Heerfordt-Waldenstrom syndrome as an initial presentation of sarcoidosis. Proc (Bayl Univ Med Cent) 2013; 26 (4): 390–392. Doi: 10.1080/08998280.2013.1192 9014.
7. Petropoulos IK, Zuber JP, Guex-Crosier Y. Heerfordt syndrome with unilateral facial nerve palsy: a rare presentation of sarcoidosis. Klin Monbl Augenheilkd 2008; 225 (5): 453–456. Doi: 10.1055/s-2008-1027356.
8. Tamme T, Leibur E, Kulla A. Sarcoidosis (Heerfordt syndrome): a case report. Stomatologija 2007; 9 (2): 61–64.
9. Takahashi N, Horie T. Heerfordt syndrome. Nihon Rinsho 2002; 60 (9): 1822–1826.
10. Srirangaramasamy J, Kathirvelu S. A Rare Case of Heerfordt‘s Syndrome with Bilateral Fa- cial Palsy. Indian J Otolaryngol Head Neck Surg 2019; 71 (Suppl 2): 1027–1029. Doi: 10.1007/s120 70-016-0964-6.
11. Otani K, Noda K, Ukichi T et al. A case of abortive type of Heerfordt syndrome associated with paralysis of trigeminal nerve. Nihon Rinsho Meneki Gakkai Kaishi 2013; 36 (2): 115–121. Doi: 10.2177/jsci.36.115.
12. Kolek V, Žurková M, Lošťáková L. Sarkoidóza – aktuální pohled na patogenezi, diagnostiku a léčbu. Kardio Rev Int Med 2019; 21 (3): 145–150.
Labels
Audiology Paediatric ENT ENT (Otorhinolaryngology)Article was published in
Otorhinolaryngology and Phoniatrics
2023 Issue 1
Most read in this issue
- Experience with secondary voice prostheses implantations at the Department of Otorhinolaryngology and Head and Neck Surgery at the Olomouc University Hospital in 2016–2021
- An accuracy of whisper hearing test together with screening otoacoustic emissions in the detection of hearing loss
- Heerfordt’s syndrom – a rare manifestation of sarcoidosis from an ENT perspective
- Functional evaluation of laryngoscopic examination and its relation to voice quality and voice range profile parameters