Importance of Neck Nodes Dissection in the Organ Preserving Protocol
Authors:
Z. Horáková
; H. Binková; E. Tóthová
Authors‘ workplace:
Klinika ORL a chirurgie hlavy a krku FN u sv. Anny, Brno, přednosta prof. MUDr. R. Kostřica, CSc.
Published in:
Otorinolaryngol Foniatr, 59, 2010, No. 1, pp. 19-27.
Category:
Original Article
Overview
In the following study we were evaluating a benefit of a neck dissection as a part of an organ preserving protocol. In patients with local advanced head and neck carcinoma we correlated clinical and histopathological response of neck metastases to the chemoradiotherapy. In 42% the microscopic persistence was confirmed. The correlation to the clinical finding was limited.
Its influence on neither over all survival nor disease-free interval was not significant in comparison to the control group without neck dissection. We confirmed an influence of persistent neck metastases on disease free interval.
Key words:
neck dissection, chemoradiotherapy, organ preserving protocol, lymph node metastasis, head and neck cancer.
Sources
1. Allal, A., Dulguerov, P., Bieri, S.: A conservation approach to pharyngeal carcinoma with advanced neck disease: optimizing neck management. Head Neck, 21, 1999, s. 217-222.
2. Armstrog, J., Pfister, D., Strong, E.: The management of the clinically positive neck as part of a larynx preservation approach. Int. J. Radiation Oncology Biol. Phys.,, 26, 1993, s. 759-765.
3. Brizel, D., Prosnitz, R., Hunter, S. et al.: Necessity for adjuvant neck dissection in setting of concurrent chemoradiation for advanced head and neck cancer. Int. J. Radiation Oncology, 58, 2004, s. 1418-1423.
4. Farrag, T., Lin, F., Cummings, Ch. et al.: Neck management in patients undergoing postradiotherapy salvage laryngeal surgery for recurrent persistent laryngeal cancer. Laryngoscope, 116, 2006, s. 1864-1866.
5. Frank, D., Hu, K., Culliney, B. et al.: Planned neck dissection after concomitant radiochemotherapy for advanced head and neck cancer. Laryngoscope, 115, 2005, s. 1015- 1020.
6. Johnson, C., Silverman, L., Clay, L.: Radiotherapeutic management of bulky cervical lymphadenopathy in squamous cell carcinoma of the head and neck: is postradiotherapy neck dissection necessary? Radiat. Oncolinvest., 6, 1998, s. 52-57.
7. McHam, S., Adeistein, D., Rybicki, L. et al.: Who merits a neck dissection after definitive chemoradiotherapy for N2-N3 squamous cell head and neck cancer? Head Neck, 25, 2003, s. 791-98.
8. Mendenhall, W., Villaret, D., Amdur, R. et al.: Planned neck dissection after definitive radiotherpy for squamous cell carcinoma of the head and neck. Head neck, 24, 2002, s. 1012-1018.
9. Narayan, K., Crane, Ch., Kleid, S. et al.: Planned neck dissection as an adjunct to the management of patients with advanced neck disease treated with definitive radiotherapy: for some or fol all. Head Neck, 21, 1999, s. 606-613.
10. Ojiri, H., Mendenhall, W., Stringer, S. et al.: Post RT CT results as a predictive model for the necessity of planned post RT neck dissection. Int. J. Radiation Oncology, 52, 2002, s. 420-428.
11. Roy, S., Tibesar, R., Daly, D.: Role of planned neck dissection for advanced metastatic disease in tongue base or tonsil squamous cell carcinoma treated with radiotherapy. Head Neck, 24, 2002, s. 474-481.
12. Sewall, G., Palazzi-Churas, K., Richards, G., Hartig, G.: Planned postradiotherapy neck dissection: rationale and clinical outcomes. Laryngoscope, 117, 2007, s. 121-128.
13. Stenson, K., Huo, D., Blair, E.: Planned post-chemoradiation neck dissection: significance of radiation dose. Laryngoscope, 116, 2006, s. 33-36.
Labels
Audiology Paediatric ENT ENT (Otorhinolaryngology)Article was published in
Otorhinolaryngology and Phoniatrics
2010 Issue 1
Most read in this issue
- Reflux Finding Score
- Importance of Neck Nodes Dissection in the Organ Preserving Protocol
- Bipolar Coagulation BiClamp® in the Operation on Thyroid Gland
- Late Results of Cholesteatoma Surgery in Children