Inflammatory myofibroblastic tumour in otorhinolaryngology
Authors:
Lucie Zeinerová 1
; Michal Černý 1,2
; Jan Laco 2,3
; Dědková J. 4; Viktor Chrobok 1,2
Authors‘ workplace:
Klinika otorinolaryngologie a chirurgie hlavy a krku, FN Hradec Králové
1; Univerzita Karlova, LF v Hradci Králové
2; Fingerlandův ústav patologie, FN Hradec Králové
3; Radiologická klinika, FN Hradec Králové
4
Published in:
Otorinolaryngol Foniatr, 71, 2022, No. 1, pp. 38-43.
Category:
Case Reports
doi:
https://doi.org/10.48095/ccorl202238
Overview
Introduction: Inflammatory myofibroblastic tumour (IMT) is a rare tumour with borderline biological behaviour composed of fibroblasts and myofibroblasts and accompanied by non-neoplastic inflammatory cells. It occurs mostly in children and young adults. The disease is most commonly seen in abdominal soft tissues (omentum, mesentery, etc.), in the lungs and also has been reported in other parts of gastrointestinal tract and other organs. In the head and neck region IMT is not so common, it may occur in larynx, trachea or nasal sinuses. The primary therapeutic approach is a complete surgical excision. Radiation, chemotherapy or biological treatment modalities are used in aggressive, non-resectable, and recurrent tumours or in case of metastases. Aims: Through a case report on a small set of patients and up-to-date information from the literature, the authors want to share knowledge about the rare diagnosis of IMT in ENT, its possible clinical manifestations, differential diagnosis and appropriate treatment. The group of patients, the case report: The paper presents patients with IMT treated at the Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Hradec Kralove in the years 2013–2020. The case of a 11-year-old boy with progressive dyspnoea caused by polypoid tracheal tumour is discussed in more detail. The tumour was removed by external surgical approach with bronchoscopy assistance. Histological examination proved an IMT. Conclusion: IMT is a rare neoplasm which must be included in the differential diagnosis of tumours of the respiratory tract, especially in children and young adults. The treatment consists of complete surgical removal and regular follow-up due to the risk of local recurrence.
Keywords:
inflammatory myofibroblastic tumour – dyspnoea in a child – tracheal tumour
Sources
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Labels
Audiology Paediatric ENT ENT (Otorhinolaryngology)Article was published in
Otorhinolaryngology and Phoniatrics
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