Clinical experience with the treatment of inverted papilloma at the Department of Otorhinolaryngology and Maxillofacial Surgery of the 3rd Faculty of Medicine, Charles University and Central Military Hospital between 2013– 2023

Overview

Introduction: Inverted papilloma (IP) is a benign tumor of the nasal cavity and paranasal sinuses (PNS) that typically manifests unilaterally, peaks in incidence in 50–60 year-olds, and is more common in men. An endoscopic examination, including biopsy and imaging to ascertain the tumor‘s extent, is part of the diagnosis. IP is mainly treated surgically, with endoscopic endonasal resection being the preferred procedure. Methods and materials: In total, 34 IP patients in our group between 2013 and the end of 2023 were retrospectively analysed. Approximately 94% of them experienced unilateral incidence. The maxillary cavity and lateral wall of the nasal cavity were the tumor‘s most frequent locations. Results: Endoscopic IP resection was utilized in 42% of the procedures in our group. Combined or external procedures were used for larger tumors or recurrences. Within two years following surgery, 52% of patients experienced a recurrence of IP. Of the total number of patients, 26% experienced one recurrence, and 10% experienced more than one recurrence throughout the monitored period. Conclusions: For the treatment of IP, the radicality of the procedure (negative resection margine) is crucial. Long-term follow-up is advised to lower the chance of recurrences and to distinguish any potential malignant transformation.

Keywords:

inverted papilloma – Endoscopic surgery – retrospective study