Respiratory Epithelial Adenomatoid Hamartoma
Authors:
Jana Krtičková 1
; J. Laco 2; Jana Dědková 3; J. Vodička 4; Jana Šatanková 1
; Anna Švejdová 1
; J. Růžička 1; P. Kordač 1
; P. Čelakovský 1; Jan Mejzlík 1
; L. Školoudík 1; Viktor Chrobok 1
Authors‘ workplace:
Klinika otorinolaryngologie a chirurgie hlavy a krku, Fakultní nemocnice Hradec Králové, Univerzita Karlova, Lékařská fakulta v Hradci Králové
1; Fingerlandův ústav patologie, Fakultní nemocnice Hradec Králové, Univerzita Karlova, Lékařská fakulta v Hradci Králové
2; Radiologická klinika, Fakultní nemocnice Hradec Králové, Univerzita Karlova, Lékařská fakulta v Hradci Králové
3; Klinika otorinolaryngologie a chirurgie hlavy a krku, Nemocnice Pardubického kraje, a. s., Pardubická nemocnice, Fakulta zdravotnických studií, Univerzita Pardubice
4
Published in:
Otorinolaryngol Foniatr, 68, 2019, No. 4, pp. 211-216.
Category:
Original Article
Overview
Introduction: Respiratory epithelial adenomatoid hamartoma (REAH) belongs to the group of benign sinonasal lesions, manifesting as an isolated lesion or in coincidence with chronic rhinosinusitis with polyps.
Objective: Herein, we present clinical data of our REAH patients and provide an overview of the literature on the subject.
Materials and Methods: Retrospective analysis of age, sex, symptoms, imaging examination, operation methods, and recurrence.
Results: During the period 2013–2018, six REAH patients aged 48–76 (median 61.5 years) were diagnosed at the Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Hradec Kralové. Before the diagnosis of REAH, the smell disorder was detected in five cases, nasal obstruction and secretion in five patients as well. In isolated form, REAH was found once at the posterior edge of the septum, twice in the olfactory cleft. In association with chronic rhinosinusitis with polyps, REAH was detected twice in olfactory cleft and once in ethmoids. Five patients have been operated by endonasal endoscopic surgery, four patients under general anesthesia and one patient under local anesthesia. Five patients are followed-up without recurrence (range 5 months – 5 years, median 48 months). One patient refused surgery and is not followed-up.
Conclusion: Respiratory epithelial adenomatoid hamartoma is a benign sinonasal lesion. Histological examination is essential for the differential diagnosis of lesions needing other treatment strategies. After complete surgical removal, recurrence is rare.
Keywords:
inverted papilloma – respiratory epithelial adenomatoid hamartoma – sinonasal carcinoma
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Audiology Paediatric ENT ENT (Otorhinolaryngology)Article was published in
Otorhinolaryngology and Phoniatrics
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